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Simultaneous Mass Cytometry Quantification of Multiple Targets for Biotherapeutic Drug Development

→ Speaker: Chad Stevens, MS, Pfizer Worldwide Research & Development

Stevens introduces an approach for simultaneous analysis of multiple cell surface drug target receptors in diverse cell populations based on deep immunophenotyping of human whole blood samples. This technique is being used in biotherapeutic development to inform modeling and simulation teams on target feasibility and coverage requirements at Pfizer. Such multiplex quantification of target expression provides critical information to project teams on target distribution and improves prediction models.